Detalhe da pesquisa
1.
Pharmacokinetics and safety of bilastine in children aged 6 to 11 years with allergic rhinoconjunctivitis or chronic urticaria.
Eur J Pediatr
; 179(5): 801-805, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-31919579
2.
Model Informed Pediatric Development Applied to Bilastine: Ontogenic PK Model Development, Dose Selection for First Time in Children and PK Study Design.
Pharm Res
; 34(12): 2720-2734, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28971281
3.
Integration of preclinical and clinical knowledge to predict intravenous PK in human: bilastine case study.
Eur J Drug Metab Pharmacokinet
; 39(1): 33-41, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23619917
4.
Pharmacokinetic and Pharmacodynamic Analysis of Acetaminophen and Ibuprofen Dual Therapy for Patent Ductus Arteriosus Closure in Preterm Neonates at Less Than 29 Weeks of Gestation.
J Clin Pharmacol
; 64(3): 312-322, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38015103
5.
Interspecies Brain PBPK Modeling Platform to Predict Passive Transport through the Blood-Brain Barrier and Assess Target Site Disposition.
Pharmaceutics
; 16(2)2024 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38399280
6.
PK/PD modeling and simulation of the in vitro activity of the combinations of isavuconazole with echinocandins against Candida auris.
CPT Pharmacometrics Syst Pharmacol
; 12(6): 770-782, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36915233
7.
Leveraging Physiologically Based Modelling to Provide Insights on the Absorption of Paliperidone Extended-Release Formulation under Fed and Fasting Conditions.
Pharmaceutics
; 15(2)2023 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36839950
8.
Model-Based Analysis of In Vivo Release Data of Levonorgestrel Implants: Projecting Long-Term Systemic Exposure.
Pharmaceutics
; 15(5)2023 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37242635
9.
Effect of Roux-En-Y Gastric Bypass in the Pharmacokinetics of (R)-Carvedilol and (S)-Carvedilol.
J Clin Pharmacol
; 63(7): 838-847, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36854819
10.
Key Factors in Effective Patient-Tailored Dosing of Fluoroquinolones in Urological Infections: Interindividual Pharmacokinetic and Pharmacodynamic Variability.
Antibiotics (Basel)
; 11(5)2022 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35625285
11.
Determining the Exposure Threshold for Levonorgestrel Efficacy Using an Integrated Model Based Meta-Analysis Approach.
Clin Pharmacol Ther
; 111(2): 509-518, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34674227
12.
Application of physiologically based absorption and pharmacokinetic modeling in the development process of oral modified release generic products.
Eur J Pharm Biopharm
; 176: 87-94, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35598768
13.
Development of a Translational Exposure-Bracketing Approach to Streamline the Development of Hormonal Contraceptive Drug Products.
Clin Pharmacol Ther
; 112(4): 909-916, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35723889
14.
In Vitro Synergistic Interactions of Isavuconazole and Echinocandins against Candida auris.
Antibiotics (Basel)
; 10(4)2021 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33800601
15.
In Vitro Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Amphotericin B against Candida auris.
Pharmaceutics
; 13(11)2021 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34834182
16.
Model-Informed Optimization of a Pediatric Clinical Pharmacokinetic Trial of a New Spironolactone Liquid Formulation.
Pharmaceutics
; 13(6)2021 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34201093
17.
Quantitative Assessment of Levonorgestrel Binding Partner Interplay and Drug-Drug Interactions Using Physiologically Based Pharmacokinetic Modeling.
CPT Pharmacometrics Syst Pharmacol
; 10(1): 48-58, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33217171
18.
Application of a dual mechanistic approach to support bilastine dose selection for older adults.
CPT Pharmacometrics Syst Pharmacol
; 10(9): 1006-1017, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34157202
19.
Physiologically Based Pharmacokinetic Modeling of Monoclonal Antibodies in Pediatric Populations Using PK-Sim.
Front Pharmacol
; 11: 868, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32595502
20.
Incorporating Pharmacometrics into Pharmacoeconomic Models: Applications from Drug Development.
Pharmacoeconomics
; 38(10): 1031-1042, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32734572